Coat Length, Curl and Furnishings/Improper Coat

Introduction

Coat Length:

Five recessive mutations (variants) in the fibroblast growth factor-5 (FGF5) gene are associated with long hair phenotypes in dogs. p.Cys95Phe (L) is the most common across breeds. c.578C>T (L2) occurs in Akita, Eurasier Samoyed and Siberian Husky breeds. c.556-571del16 (L3) occurs in Eurasier breed, c.559-560dupGG (L4) occurs in Afghan hound and Eurasier breeds, and g.8193T>A  (L5) occurs in Afghan hound.

The long hair test offered by the VGL screens for all 5 variants. To simplify reporting, we designated the variants as L, L2, L3, L4, L5 as indicated above.   

ORDER TEST KITS | PRICE LIST
Allow 5-10 business days for results.

Coat Length results reported as:

Test Result Coat Length (FGF5)
S/S Dog has short hair. Long-haired offspring cannot be produced.
S/L* Dog has short hair and carries long hair gene.
L*/L* Dog has long hair.

* The report will specify mutations as L, L2, L3, L4, L5.

Curl:

A recessive variant in the Keratin-71 (KRT71) is associated with curly hair in dogs. The test offered by the VGL assays the p.Arg151Trp variant in KRT71.

ORDER TEST KITS | PRICE LIST
Allow 2-6 business days for results.

Curl results reported as:

Test Result Curl (KRT71)
N/N Dog has straight coat.
N/C Dog has wavy coat
C/C Dog has curly coat.

 

Furnishings and Improper Coat:

Furnishings refers to the longer mustache and eyebrows seen in wire-haired dogs and other breeds. A dominant variant (167bp in the 3’-UTR sequence) of the R-spondin-2 (RSPO2) gene, produces this desired texture and growth pattern of fur.

Improper Coat: The breed standard for Labradoodle, Goldendoodles and Portuguese Water Dog requires “furnishings”. In these dog breeds, lack of the dominant RSPO2 variant (IC) causes Improper Coat which is characterized by short hair on the head, face and legs.

*Furnishings and Improper Coat are the same test with different interpretations.

ORDER TEST KITS | PRICE LIST
Allow 2-6 business days for results.

Furnishings results reported as:

Test Result Furnishings (RSPO2)
N/N Dog does not have furnishings.
N/F Dog has furnishings and carries 1 copy of the non-furnishing gene.
F/F Dog has furnishings. All offspring will have furnishings.

Improper Coat results reported as:

Test Result Improper Coat (RSPO2)
N/N No copies of Improper Coat, normal, dog will have longer hair on the muzzle and eyebrows.
N/IC 1 copy of Improper Coat, carrier, dog will have longer hair on the muzzle and eyebrows.
IC/IC 2 copies of Improper Coat, dog has Improper Coat, dog will NOT have longer hair on the muzzle and eyebrows.


Reference:
Cadieu E, Neff MW, Quignon P, Walsh K, Chase K, Parker HG, Vonholdt BM, Rhue A, Boyko A, Byers A, Wong A, Mosher DS, Elkahloun AG, Spady TC, André C, Lark KG, Cargill M, Bustamante CD, Wayne RK, Ostrander EA. Coat variation in the domestic dog is governed by variants in three genes. Science 326:150-153, 2009.

Veterinary Genetics Laboratory, Tel 530-752-2211, Email VGL