UC Davis School of Veterinary Medicine Veterinary Genetics Laboratory
Dairy Milk Protein Tests
Introduction

The Veterinary Genetics Laboratory offers genotyping for 3 important milk protein genes that have been shown to be associated with milk yield, total milk protein and composition.

Beta Casein is an important gene for milk production traits. The VGL test identifies the variants: A1, A2, A3, B, C, F, G, H1, H2, I, K, L. The A2 variant has been shown to have a positive association with milk yield and protein content. Based on the amino acid in position 67 these variants can be classified into 2 groups - A1 and A2. Variants that belong to the A1 group (His67) are A1, B, C, F and G. Variants that belong to the A2 group (Pro67) are A2, A3, H1, H2, I, J, K and L. The levels of bioactive peptide beta-casomorphin 7 (BCM7) produced from the metabolism of beta casein is several-fold higher for variants in the A1 group than in the A2 group. Higher levels of BCM7 have been associated with negative health effects in humans. More...

The VGL is certified by the A2 Corporation Ltd to offer a DNA test to identify animals that carry the A2 beta casein variant. For more information about A2 Corporation and A2 Milk®, visit the A2 Corporation Website

Kappa Casein is an important gene for protein yield and percentage in milk. The VGL test identifies the 2 most common variants A and B. The A variant and AA genotype are associated with higher milk production. The B variant and BB genotype are associated with increased milk protein and casein content, and better cheese yield. Relative to protein content and cheese production, BB is the most favorable genotype, AB is intermediate and AA is the least favorable.

Beta Lactoglobulin is the major whey protein gene. The VGL test identifies the 2 most common variants A and B. The A variant is associated with increased milk yield and whey protein content. The B variant is associated with increased casein and fat content and is favorable for cheese production.

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Allow 5-8 business days for results.

 
Veterinary Genetics Laboratory, Tel 530-752-2211, Email VGL