UC Davis School of Veterinary Medicine Veterinary Genetics Laboratory

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The Cream dilution gene is responsible for the palomino, buckskin, smoky black, cremello, perlino and smoky cream coat colors. There are two alleles: CCr and C. CCr is semi-dominant and dilutes red to yellow in single dose (palominos, buckskins, smoky blacks) and to pale cream in double dose (cremellos, perlinos, smoky cream). Cream dilution can have a very subtle effect on black pigment. C is recessive and does not dilute the base color.

Cream Dilution results are reported as:

N/N Non-dilute. Basic colors are chestnut, bay, black or brown in the absence of other modifying genes.
N/Cr Heterozygous, dilute, one copy of the Cream CCr allele. Chestnut is diluted to palomino; bay is diluted to buckskin and black is diluted to smoky black. These colors can be further modified by the actions of other genes
Cr/Cr Double dilute (two copies of the CCr allele). Chestnut is diluted to cremello; bay is diluted to perlino and black is diluted to smoky cream.

Note: The test offered by VGL is specific for a mutation in exon 2 of the MATP gene that is associated with Cream Dilution. Other dilution genes or mutations that may produce coat colors that phenotypically resemble cream will not be detected by the test.

Veterinary Genetics Laboratory, Tel 530-752-2211, Email VGL