Health

Equine Juvenile Spinocerebellar Ataxia (EJSCA) is an inherited neurologic disease that causes ataxia in American Quarter Horses.

Fanconi syndrome is a heritable kidney disorder that affects Basenjis. Affected dogs typically present kidney dysfunction around 4-8 years of age.

Progressive retinal atrophy (PRA) is characterized by degeneration of the retina resulting in progressive vision loss leading to total blindness. This Basenji PRA is caused by a mutation in the S-antigen (SAG) gene.

Pyruvate kinase deficiency in the Basenji is a chronic, severe hemolytic anemia caused by defective production of the enzyme pyruvate kinase. Signs in affected dogs may include lethargy, low exercise tolerance, and fatigue.

Saluki encephalopathy is a neurological disorder caused by Succinic Semialdehyde Dehydrogenase Deficiency (SSADHD) and clinically characterized by early onset of seizures and abnormal behaviors. This condition is also known as central nervous system status spongiosus in Saluki dogs (SSSD).

Congenital myotonia is a heritable neuromuscular disorder characterized by a slow relaxation of skeletal muscles following voluntary contraction. Affected foals have difficulty moving due to stiffness.

Congenital ichthyosis is a skin condition in which the outer layer of the skin does not form properly and results in scaling. The condition often progresses to large patches of thickened, black, scaly skin. A recently identified allele is associated with congenital ichthyosis in the Labrador Retriever and is referred to as congenital ichthyosis type 3 (ICH3).

Rod-cone dysplasia type 2 (rcd2) is a type of early-onset retinal degeneration that affects collie breeds and typically lead to blindness.

Spinocerebellar ataxia (also known as cerebellar ataxia or CA) is an inherited disorder that affects the Spinone Italiano and is characterized by early onset of progressive incoordination (ataxia).