UC Davis School of Veterinary Medicine Veterinary Genetics Laboratory
Genetic Diversity Testing for Berger Picard

Overview

The Veterinary Genetics Laboratory (VGL), in collaboration with Dr. Niels C. Pedersen and staff, has developed a panel of short tandem repeat (STR) markers that will assess genetic diversity across the genome and in the Dog Leukocyte Antigen (DLA) class I and II regions. This test panel will be useful to breeders who wish to track and increase genetic diversity of their breed as a long-term goal.

A DNA-based genetic assessment of the Berger Picard is now in the preliminary results phase with the objective of creating a snapshot of individual- and breed-wide genetic heterogeneity and diversity. This initial testing involved 34 Berger Picard, 30 with listed countries of origin (USA 21; France 5; The Netherlands 2; Sweden 1; Germany 1). Twenty-two dogs were involved in showing and 10 also participated in performance activities. Therefore, we believe that the 34 dogs are a reasonable cross section of the breed as it currently exists. We are accepting additional dogs from all parts of the world with a goal of 50-75 individuals to complete this preliminary phase. This data base will be progressively expanded as more dogs are added with the goal of characterizing all the known alleles for the breed at 33 STR autosomal loci and existing DLA class I and II haplotypes identified by seven additional STRs.

Price: $50.

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Results reported as:
Short tandem repeat (STR) loci: A total of 33 STR loci from carefully selected regions of the genome were used to gauge genetic diversity within an individual and across the breed. The alleles inherited from each parent are displayed graphically to highlight heterozygosity, and breed-wide allele frequency is provided.

DLA haplotypes: STR loci linked to the DLA class I and II genes were used to identify genetic differences in regions regulating immune responses and self/non-self recognition. Problems with self/non-self recognition, along with non-genetic factors in the environment, are responsible for autoimmune disease.

Internal Relatedness: The IR value is a measure of genetic diversity within an individual that takes into consideration both heterozygosity of alleles at each STR loci and their relative frequency in the population. Therefore, IR values heterozygosity over homozygosity and uncommon alleles over common alleles. IR values are unique to each dog and cannot be compared between dogs. Two dogs may have identical IR values but with very different genetic makeups.

Report

Report issued September 26, 2019. Daily updated statistics are here.

Veterinary Genetics Laboratory, Tel 530-752-2211, Email VGL